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In clinical trial data, nausea, diarrhoea, constipation and vomiting are consistently among the most common side effects

Post-Inflammatory Hyperpigmentation (PIH): PIH occurs as a result of inflammation or injury to the skin caused by acne, eczema, psoriasis, or allergic reactions

However, no randomized controlled trials have tested whether adding glutathione to GLP-1 therapy improves outcomes beyond semaglutide alone

14 In contrast, Weschawalit et al 3 reported a statistically significant effect of glutathione as a skin-lightening agent, but this was limited to a group of participants aged older than 40 years who received GSH, a reduced form of glutathione, on the sun-exposed area of the right forearm